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Multivariate analysis showed no difference between placebo and liraglutide arms in HbA1c at 6 months (HbA1c:0.2mmol/mol, 11.3, 11.6, p=0.98) however, at 12 months HbA1c was significantly higher in the liraglutide arm (HbA1c:10.9mmol/mol, 1.1, 20.6, p=0.032)

She also explained that rapid weight loss can come with downsides, including muscle loss, hair shedding, fatigue, and nutrient deficiencies

This diet not only ameliorates insulin resistance and maintains a healthy body weight but also regulates immunomodulation, enhances gut microbiome diversity and provides essential phytonutrients, collectively preventing inflammation

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However, their exact effects remain unclear

1 Competitive Landscape: Two Leaders, Several Strong Contenders Innovent Biologics mazdutide has already been approved, giving Innovent a clear first-mover advantage