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Patients living in countries outside of the USA may be able to obtain larger volumes, such as a one-year supply, to be shipped

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Whilst there is no confirmed causal link between retatrutide and depression, certain individuals may be more vulnerable to mood changes during any significant pharmacological intervention, particularly one that produces rapid and substantial weight loss

This hypothesis is supported by the finding that GLP-1 induced CICR does not occur in the presence of a VDCC-inhibitor, nifedipine [49]