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25 Gly 35,37 Substitution of Gly 35 for Aib, together with introduction of Aib at position 8, resulted in a potent analog called taspoglutide ( 3 )

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Magnus Simrn is Professor of Gastroenterology at the Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

They work by mimicking the action of naturally occurring GLP-1, an incretin hormone released from the intestine in response to food intake