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In an email to CBC News, Health Canada said it "authorized the drug after a thorough review of evidence provided by the company demonstrating that the drug meets Health Canada's criteria for safety, effectiveness and quality for generic drugs." It continued to say that generic semaglutide drug submissions are complicated, and the manufacturer must show that any differences do not affect the drug

Now, Lilly recently reported topline results from the ATTAIN-1 phase-3 trial evaluating orforglipron, a once-daily oral glucagon-like-peptide-1 (GLP-1) receptor agonist for adults with obesity or overweight without diabetes

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To minimise GLP-1 side effects, these medications are typically prescribed with a process called dose titration starting at a very low dose and gradually increasing it over several weeks to give your body time to adapt