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Individuals were followed from index date until the first stroke event (for the primary outcome analysis), end of enrolment in their insurance plan or the end of the study period (30 September 2020), whichever was earliest

Three models were constructed: Model 1 (crude model), Model 2 (adjusted for age and sex), and Model 3 (fully adjusted for potential confounders including BMI, blood pressure, lipid profile, renal function, osteocalcin (OCN), vitamin D levels, HbA1c, statin use, antihypertensive medication use, and smoking status)

Selection bias may have affected the generalizability of our findings

Collectively, these findings demonstrate sustained Exe4 expression and secretion by the liver following a single in vivo genome editing at the mouse Alb locus using LNP-mediated HITI, with no discernible side effects

S., Boutron I., et al

W aktualnym ChPL Wegovy opisano take wane ostrzeenia praktyczne: ryzyko zachynicia podczas znieczulenia oglnego lub gbokiej sedacji (zwizane z opnionym oprnianiem odka), ryzyko odwodnienia przy nasilonych objawach z przewodu pokarmowego oraz ostrzeenia dotyczce ostrego zapalenia trzustki