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Bridging the gap between guidelines and practice will require systemic interventions, including physician training, patient-centered care models, and devising research strategies such as national HF registries to understand and tailor therapeutic approaches from an Indian perspective.

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While tirzepatide appears to provide greater weight loss than semaglutide in this population, head-to-head RCTs are not yet available.

Newly conducted research suggests that metabolic disorders, like diabetes and obesity, play a significant role as risk factors for psychiatric disorders