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Description
148 Hence, IR promotes the pathology of AD by reducing amyloid clearance and increasing tau hyperphosphorylation neurofibrillary tangles, 149 both of which are associated with cognitive impairment
At present, several oral antidiabetic medications are used for the treatment of T2DM including, -glucosidases inhibitors, biguanides, sulfonylureas, meglitinides, GLP-1 receptor agonists (GLP-1RAs), peroxisome proliferator-activated receptor (PPAR-) agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodiumglucose transporter 2 (SGLT2) inhibitors
In: Post T, ed
AACE Clin Case Rep 5(3):e197e200
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Several real-world studies based on administrative data and pharmacy reports have demonstrated that reduced adherence to antidiabetic therapy is associated not only with poorer glycemic control but also with a significant increase in overall mortality and hospitalizations for all causes [70, 71]
