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Meier JJ, Gethmann A, Gtze O, Gallwitz B, Holst JJ, Schmidt WE, et al

Triggers for initiating a discussion on switching may include HbA 1c targets not being met, the need for additional weight loss, patients moving to an increased cardiovascular risk status and poor adherence

In patients with MASLD and established CVD, GLP-1-based therapies are strongly supported as a cornerstone treatment addressing both hepatic and cardiometabolic disease burden simultaneously

Exenatide (Byetta and Bydureon, AstraZeneca), is a synthetic 39-amino acid peptide (first discovered as exendin-4 in the saliva of the gila monster, Heloderma suspectum) (Figure 8) [879]

When calorie intake decreases significantly, protein consumption often drops as well

Effect of the dual glucosedependent insulinotropic peptide/gulcagonlike peptide 1 receptor agonist tirzepatide on lipid profile and waist circumference: a systematic review and metaanalysis