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Most evidence-based obesity pharmacotherapy criteria commonly used: BMI 30, or BMI 27 with a weight-related comorbidity Why BMI isnt the whole story: BMI doesnt show visceral fat, fatty liver risk, glucose variability, or cardiometabolic risk

Most dual-compound research focuses instead on combining tirzepatide with other peptide classes (e.g., glucagon receptor agonists or amylin analogs) or stacking low-dose tirzepatide with oral semaglutide to balance efficacy and tolerability

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Clinical Studies and Real-Life Results 5.1 Research on Tirzepatide and Sleep Improvement While Tirzepatide is primarily known for its effects on weight loss and blood sugar control, research is beginning to explore its potential to improve sleep quality

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