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If prescribed, patients may receive educational resources on proper preparation and administration

[DOI] [PubMed] [Google Scholar] 52.Horowitz M, Aroda VR, Han J, Hardy E, Rayner CK

Moreover, the long-term effects of therapeutic GIP receptor antagonism in humans are not fully elucidated and are thought to depend on the specific drug molecule, receptor functions, and the extent of GLP-1 receptor activation

They provide an anti-inflammatory benefit, largely because they help reduce visceral (intra-abdominal) fat, which is itself, highly inflammatory tissue

This alteration of the microbiota may partly explain the variability in GLP-1RA responsiveness and presents opportunities for combination therapy using probiotics or prebiotics to augment therapeutic effectiveness