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An FR schedule is an operant reinforcement protocol where a specific, constant number of responses is required to obtain each unit of reinforcement
They are distinguished by their capability to produce elevated levels of pro-inflammatory cytokines, including IL-1, IL-6 and TNF- [79]
It works best when combined with a balanced diet, regular physical activity, and other healthy lifestyle habits
Scheme 7
10.1056/NEJMoa1901118 60
