glp 1 for kidney disease Renal effects of GLP-1 receptor agonists and tirzepatide in individuals with type 2 diabetes: seeds of a promising future | Endocrine Real-World Evidence for GLP-1 Receptor

International Journal of Molecular Sciences 24

It is believed that untreated/ uncontrolled/poorly treated diabetes can cause damage to blood vessels, including vessels in the brain

GLP-1 medications are not recommended for people with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)

The expression of GLP-1 receptors in eosinophils in asthma patients was significantly lower than in healthy peoples eosinophils, while the number of GLP-1 receptors in neutrophils was the same in both populations

As is the case with azelaprag, we currently have no idea how these medications will perform in people taking weight-loss drugs, either

The SURMOUNT-5 head-to-head trial directly compared Zepbound to Wegovy, with results published in The New England Journal of Medicine: The addition of GIP receptor activation unlocks approximately 6% additional fat loss compared to GLP-1-only medications, while also helping preserve muscle mass better