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Shared Effects Both medications can reduce appetite, increase fullness, and slow digestion

Nausea, Dehydration, and Gastrointestinal Side Effects Nausea ranks among the most common side effects of semaglutide, affecting up to 40% of users during dose escalation

These FDA-approved weight loss medications can help control your appetite, reduce cravings, and boost your bodys sugar metabolism

Afterwards, the daily glucose levels remained consistently within the range 80140 mg/dL, without significant hyperglycemic episodes and with rare hypoglycemic episodes

References (this section): NEJM (2023): Phase 2 trial publication Eli Lilly: Phase 2 results (mentions 24.2% at 48 weeks as a secondary endpoint) Eli Lilly (Dec 2025): Phase 3 TRIUMPH-4 topline results announcement Retatrutide side effects: what trials report (not medical advice) Searches like retatrutide side effects and side effects of retatrutide usually refer to events reported in clinical trial publications and sponsor summaries