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Benefits are most evident in metabolic dysfunction, where they reduce physiological stress and complement lifestyle measures without directly modifying primary aging mechanisms

Amruta Prabhu +2 more Table of Contents Introduction Diabetes continues to be a major public health concern in India

Over the past five years, this convergence has driven extraordinary optimism that GLP-1s might meaningfully diminish dementia risk and perhaps even alter disease progression trajectory to a greater extent than other common diabetes medications [3]

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[DOI] [PubMed] [Google Scholar] Nolte W

52 Orforglipron showed to have a pharmacodynamic and safety profile similar to that of injectable GLP-1 which supported continued clinical development
