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Cell Biochem 114 , 844853 (2013)
JMIR Aging

The drugs success played a pivotal role in Novartis raising its 2024 earnings guidance for the third time

Although rates of adverse effects differ between specific agents, the most common adverse effects with the GLP- 1 RA class are gastrointestinal (GI)related

doi:10.1056/NEJMoa1307684 245
The spectrum ranges from simple steatosis (fat accumulation without significant inflammation) to nonalcoholic steatohepatitis (NASH), which involves inflammation and hepatocyte injury that can progress to fibrosis, cirrhosis, and hepatocellular carcinoma