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Abbreviations DPP-4: Dipeptidyl peptidase 4 CGM: Continuous glucose monitoring T2DM: Type 2 diabetes mellitus d-ROMs: Diacron-reactive oxygen metabolites DTSQ: Diabetes Treatment Satisfaction Questionnaire CVD: Cardiovascular disease GLP-1RA: Glucagon-like peptide-1 receptor agonist HbA1c: Glycated hemoglobin BW: Body weight FPG: Fasting plasma glucose SD: Standard deviation MGL: Mean glucose level MAGE: Mean amplitude of glycemic excursions MODD: Mean of daily difference of blood glucose TAR: Time above range TIR: Time in range BMI: Body mass index HDL-C: High-density lipoprotein cholesterol LDL-C: Low-density lipoprotein cholesterol eGFR: Estimated glomerular filtration rate %CV: Percentage coefficient of variation for glucose References Rawshani A, Rawshani A, Franzn S, Eliasson B, Svensson AM, Miftaraj M, et al

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The multiple hit hypothesis has emerged as the dominant theory in recent years, indicating the collective impact of immunological mechanisms in the liver, intestines, and adipose tissue on the progression of MASLD [13]