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Thus, the phenotypes of PAR2 mutant mice with differential protease sensitivity indicate a critical role for selective protease activation of PAR2 in regulating metabolism in DIO

Kaku K, Rasmussen MF, Clauson P, Seino Y

Free Radic Biol Med 176:1633 Baskerville KA et al (2008) Aging elevates metabolic gene expression in brain cholinergic neurons

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