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Bratulic, Lillys Q1 revenue surge overshadowed by CVS dumping Zepbound for Wegovy | FirstWord Pharma, FirstWord Pharma (2025)

Semaglutide has a half-life of about 7 days (168 hours), which is why you only need to inject once weekly

women of childbearing age should plan contraception or discontinue the medication before conception
Often not covered by private insurance companies or government funded healthcare means many patients have no choice but to either go without or rationalise their use

Endocrinology 149 , 60186027 (2008)
For many patients, these symptoms diminish over time as the body adapts to the medication, as noted in the Summaries of Product Characteristics (SmPCs)
