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Abbreviations ADA: American Diabetes Association ARDS: Acute respiratory distress syndrome COVID-19: Coronavirus disease 2019 CRP: C-reactive protein CVD: Cardiovascular disease CVOTs: Cardiovascular outcome trials EASD: European Association for the Study of Diabetes ICU: Intensive care unit GLP-1RAs: Glucagon-like peptide-1 receptor agonists MACE: Major adverse cardiovascular event REWIND: Researching Cardiovascular Events with a Weekly Incretin in Diabetes Trial SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2 WHO: World Health Organization References Lau H, Khosrawipour V, Kocbach P, Mikolajczyk A, Ichii H, Schuburt J, et al

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To adjust the impact of baseline HbA1c concentration on decreased blood glucose concentrations, GLP-1 RA responders were defined as an HbA1c reduction ratio [(HbA1c level at week 12) (HbA1c level at baseline)/(HbA1c level at baseline)] 0.12, whereas GLP-1 RA non-responders were defined as an HbA1c reduction ratio 99% and E value = 0 (access date: Jan 23, 2021) ( igraph and SpiecEasi were used for construction of the co-occurrence network with SparCC correlation coefficients (3739)

Impact of Obesity on Breast Cancer Outcomes Obesity has a well-documented negative impact on BC outcomes through multiple biological and clinical pathways

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