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In the STEP 5 study, participants taking semaglutide lost an average of 15.2% of their body weight over two years, compared with 2.6% in the placebo group

[ 5-7] Every major drug company is currently devoting significant resources to developing more GLP-1 agonists alone or coupled with other active hormone-like compounds

104,107 Other references considered that GLP-1RAs were more likely to cause nausea and headache than metformin

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