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The 2.5 mg starting dose exists for tolerability, not effect
[DOI] [PubMed] [Google Scholar] 8.Komatsu R, Matsuyama T, Namba M, Watanabe N, Itoh H, Kono N, Tarui S

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TRAILBLAZER-ALZ 3 (NCT05026866) is a placebo-controlled phase 3 prevention trial that was started in August 2021

We have more options now, but two of the four new drugs on the market (Qsymia and Contrave) have struggled for a lack of commercial success

The approved formulation is a subcutaneous injection available in six dosages: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg ATEOS, with the non-proprietary name Tirzepatide (referred to as "Mounjaro")
