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Description
TTE: Trasns-mitral PW Doppler D

Rapid effects of ovarian hormones in dorsal striatum and nucleus accumbens
The effect is most pronounced in patients with higher starting blood pressure and concurrent obesity

Body weight was notably lower in PIONEER 9 and 10, which ranged from 68.0 kg to 74.7 kg, compared to the other PIONEER trials where the mean body weight was between 84.6 kg and 95.5 kg

Efficacy for weight loss: While Rybelsus can promote weight loss as a secondary benefit, weight loss medications like Wegovy and Saxenda have shown greater average weight loss in clinical trials due to their higher dosages and specific formulation for this purpose

They found that Victoza, whether used alone or with other diabetes pills, was as good as or even better at lowering blood sugar than other widely used diabetes drugs like sulfonylureas and thiazolidinediones
