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Exposures Two cohorts were assembled, with the first composed of patients who started and continued on GLP-1 receptor agonists or DPP-4 inhibitors between 1 January 2007 and 31 December 2020 and the second composed of patients who started and continued on GLP-1 receptor agonists or SGLT-2 inhibitors between 1 January 1 2013 and 31 December 2020

These medications, known for treating diabetes and promoting weight loss, may have unexpected benefits for those with migraine disease and headache disorders.

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GLP-1 weight-loss drugs like semaglutide have taken the world by storm, but some studies have raised concerns about side effects, including kidney injury and skeletal muscle wastage