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GLP-1 receptor agonists, the drug class that includes semaglutide (sold as Ozempic and Wegovy), appear to reduce cravings, lower overdose risk and decrease substance use disorder diagnoses in

(27) Additionally, GLP-1 agonists were linked to lower hospitalization rates, mortality, and a reduced risk of lower limb amputation (HR: 0.83, 95% CI: 0.671.03)
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FDA-Approved Eligibility Criteria: Primary Qualification (BMI-Based): You qualify if: BMI 30 (obesity category), OR BMI 27 (overweight category) PLUS at least one weight-related health condition BMI Reference Guide: Weight-Related Health Conditions (For BMI 27-29.9): Qualifying conditions include: Type 2 diabetes or prediabetes Hypertension (high blood pressure) High cholesterol or dyslipidemia Obstructive sleep apnea Cardiovascular disease Polycystic ovary syndrome (PCOS) Non-alcoholic fatty liver disease Osteoarthritis exacerbated by weight If you have BMI 27-29.9 with any of these conditions, you qualify
