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Patients with chronic hyperglycemia may have a significant negative effect on bone mass

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Sanyal and other researchers are studying several GLP-1 receptor agonists and related drugs as potential treatments that might help halt, improve or even reverse the damage caused by MASH

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However, in a co-agonist molecule, glucagon receptor activation occurs alongside GLP-1 and, in the case of retatrutide, GIP receptor activation