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9 , 10 Many patients struggle to maintain the necessary behavioral changes long term, leading to modest results which are often inadequate in addressing the complex physiological, genetic, and environmental factors underlying obesity

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From our hunter-gatherer days till relatively modern times, we went through cycles of feast and famine, and our bodies evolved to hold onto the calories we took in during times of plenty to sustain us through the times when food was scarce or nonexistent

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