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Payne recommends one thing that could make the effort easier: Dont try it alone

LPL: lipoprotein lipase

Isoprenoid derivatives of lysophosphatidylcholines enhance insulin and GLP-1 secretion through lipid-binding GPCRs

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This is due to the medications dual action: it mimics the GLP-1 hormone to signal fullness to the brain while simultaneously slowing down gastric emptying

Many users start with a lower dose to minimize side effects, which might not be enough to significantly suppress appetite initially
