natural glp 1 receptor agonists PDB-101: Molecule of the Month: GLP-1 Understanding GLP-1 receptor agonists and
Description
The real magic occur upstream of that
Key end points included: hospitalisation, heart failure (ICD-10-CM-I50), myocardial infarction (ICD-10-CM-I21), stroke and transient ischaemic attack (ICD-10-CM-I63, G45), development of diabetic microvascular complications (ICD-10-CM-E10.210.4) and all-cause mortality analysed 3 months to 5 years post drug initiation
Secondary endpoints included the rate of patients with a weight loss of 10%, monthly headache days (MHD), the rate of patients with a 30% and 50% reduction in MHD, visual outcome parameters, and adverse events (AEs)
Medline, Embase and Cochrane, to search for studies during pregnancy and/or lactation with maternal exposure to a GLP-1 agonist or an SGLT2 inhibitor ( Supplement 46 )
Interestingly, a triple GLP-1/GIP/glucagon receptor agonist was found to have neuroprotective effects on a transgenic mouse model of Alzheimers disease, as drug treatment increased neurogenesis and reversed memory deficit
Ma Y, Lee E, Yoshikawa H, Noda T, Miyamoto J, Kimura I, et al
