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According to Moffat, the short answer is that although many smart people have made many hypotheses about why numbers are increasing in the age 25-50 cohort, research doesnt point to any particular reason why these numbers are increasing
Taking thyroid medication first thing in the morning on an empty stomach and waiting 30-60 minutes before eating or taking other medications helps minimize this interaction
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Notably, lixisenatide users had the highest risk, with a hazard ratio of 2.002 (95% CI: 1.3023.079) compared to DPP-4i users
doi: 10.1053/j.gastro.2018.02.011
