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March-April 2015

This post hoc analysis examined CV effects of semaglutide in subjects across a continuum of baseline CV risk

It is a cultural shorthand that emerged as GLP-1 medications like Semaglutide and Tirzepatide became mainstream weight loss tools

Clinical and pre-clinical osteoarthritis research suggests that semaglutide reduces pain scores and cartilage loss over 2 years, compared to placebo [1], and pre-clinical research showed that a similar drug (liraglutide) reduced fibrosis of the joint synovium and reduced pain severity, despite no difference in weight-loss compared to the control groups [1]
