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Description

However, this outcome fell short of the anticipated 25% weight reduction, potentially limiting its competitive edge against Eli Lillys ZEPBOUND, which reported up to 20.9% weight loss in the SURMOUNT-1 trial. In the subsequent REDEFINE 2 trial, which focused on adults with obesity or overweight and type 2 diabetes, CagriSema achieved a 15.7% mean weight loss after 68 weeks, compared to 3.1% with placebo

The Bottom Line GLP-1 medications are a powerful tool - but they are not a complete solution

However, the beneficial clinical outcomes must be weighed against gastrointestinal (GI) side effects, high costs, and shortages that can limit access to use (2)

Most Popular Body Contouring Procedures After GLP-1 Weight Loss The surge in GLP-1-related weight loss has shifted which procedures patients request most frequently