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Cognitive decline and dementia in diabetes mellitus: Mechanisms and clinical implications

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Huang X, Wu Y, Ni Y, Xu H, He Y

GLP-1 receptors are in the pancreas and in other tissues including the gut and brain, so effects extend beyond glucose control to appetite centers and peripheral tissues related to metabolism

Although the study populations were not using medical weight reduction drugs, lower meal frequency and earlier caloric intake were associated with greater weight reduction, suggesting this approach could complement GLP-1RA treatment