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It works by irreversibly blocking the hydrogen-potassium ATPase enzyme system (the proton pump) in gastric parietal cells, thereby decreasing acid secretion into the stomach

[DOI] [PubMed] [Google Scholar] 42.Nielsen M.J., Nedergaard A.F., Sun S., Veidal S.S., Larsen L., Zheng Q., Suetta C., Henriksen K., Christiansen C., Karsdal M.A., et al
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