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Short-term safety profile (up to 68 weeks) shows side effects consistent with other incretin medications plus a new signal for dysesthesia

Although Wegovy for weight loss is not directly linked to hypoglycemia, patients who are taking other blood sugar-lowering medications may be at increased risk of hypoglycemia and should consult their provider before starting Wegovy

A., Schwartz, T

Female participants averaged 25.3% weight loss at 48 weeks while males averaged 22.8% at the same dose

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administration of GLP1 receptor agonists in laboratory animals is at least partly mediated by peripheral GLP1 receptors, presumably reflecting a major route/mechanism of action of endogenous peripheral GLP1