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Instead, mRNA expression is detected in myenteric ganglia in the intestinal mucosa, which are excitable by GLP-1 treatment ex vivo (64% synaptic and 36% after-hyperpolarizing types) (Figure 1 and Table 2)

In relation to gastroparesis, we observed 4 genes shared among all drugs GHSR, CCK, GHRL, and INS, and 12 genes shared between GLP1R/GIPR/GCGR, GLP1R/GIP, and GLP1R/GIPR: GHSR, REM1, HTR7, PHF20, MLNR, CCK, HTR3A, GHRL, ATP12A, HTR4, MLN, and INS

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