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Medication effect sizes were mostly small (by convention, Cohen d = 0.20) through week 4 and increased during weeks 5 to 8, with large effect sizes (defined as d = 0.80) observed for drinks per drinking day and heavy drinking days

Wales, S.E

CRC Press, 2016

"The Surgeon General's Call to Action to Prevent Skin Cancer" (PDF)

Your doctor may adjust your prescription if this is the cause

Weight and metabolic changes vary considerably between individuals
