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In SUSTAIN 9, mean weight loss was -4.7% with semaglutide 1.0 mg versus -1.0% with placebo from baseline to week 30

Autopsy studies indicate a surprising frequency ranging from 0.01 to over 2.0% (110,111).A survey of consecutive autopsies at Grace-New Haven Hospital found 2.7% of thyroids to harbour unsuspected thyroid cancer (111)

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It has the potential to offer numerous insights, including improved understanding of disease pathophysiology, delineation of mechanisms of action for current treatment strategies, development of biomarkers to predict treatment response and disease progression, and identification of novel therapeutic targets 7

It works by mimicking the action of the GLP-1 hormone, which is released in the gut
