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Tirzepatide , on the other hand, is a dual agonist that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

As a result, many older adults faced steep outofpocket costs

Reference 3: Cryan JF, O'Riordan KJ, Cowan CSM, et al

doi: 10.2337/dc06-2593 196 CaiYWeiLMaLHuangXTaoALiuZet al

However, no significant difference in eGFR was observed between tirzepatide and comparators

Published July 22, 2025
