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The short answer Nausea is one of the most common side effects we see with Wegovy, Zepbound, and other GLP-1 medications, and it is one of the most common reasons patients consider stopping

Furthermore, GLP-1 analogs improved plasma insulin levels, HOMA-IR, cholesterol levels, and markers of liver damage (AST and ALT), as well as reduced liver hypertrophy

Kahle MD, PhD To view or add a comment, sign in More Relevant Posts We're excited to announce positive topline data from the ACCESS clinical program of aleniglipron, an orally-available, once-daily, nonpeptide small molecule agonist of the #GLP1 receptor, for the treatment of people living with #obesity and/or overweight with at least one weight-related comorbidity

However, dual GIP and GLP-1 receptor agonists showed better efficacy with regard to glucose control and weight loss with an acceptable safety and tolerability profile [3]

The total number of BBB complaints (15 as of the most recent check) is relatively small compared to the claimed 100,000+ patient base, but the nature of the complaints, particularly the expired medication issue, is more important than the quantity

Those studies can show patterns, but they do not answer every real-world question