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The most commonly-reported side effects of GLP-1 pills are consistent with GLP-1 injections and include gastrointestinal issues such as nausea, vomiting and diarrhea, according to the trials

Both drug classes lower glucose concentrations (though through distinct mechanisms) without excess risk for hypoglycaemia, reduce body weight and albuminuria and prevent cardiovascular events, but they have opposing effects on glucagon secretion which is augmented by SGLT-2 inhibitors but suppressed by GLP-1 receptor agonists

The discussion dives into the importance of biomarkers like high-sensitivity C-reactive protein (hs-CRP) in guiding treatment strategies, the insights gleaned from landmark trials like the JUPITER and CANTOS studies, and the future of targeted anti-inflammatory therapies in cardiology

But the medications do not biologically impact allergy pathways (IgE, mast cells, eosinophils)

[DOI] [PubMed] [Google Scholar] 132.Coskun T, Sloop KW, Loghin C, Alsina-Fernandez J, Urva S, et al

Even if it's not syncope or lightheadedness if it's tachycardia, chest pain, or new shortness of breath all of these things should probably be checked
