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Description
An increased risk of arthritis was not expected, says study co-author Ziyad Al-Aly, M.D., director of the Clinical Epidemiology Center at Washington University School of Medicine in St

& DeGrado, W

GLP-1 stands for glucagon-like peptide-1 receptor agonist medications, usually administered in the form of a subcutaneous injection
It had also been discounted for the treatment of obesity because there was some prec-clinical evidence to suggest it was linked with weight gain

Structures of the glucagon receptor (GCGR), the closest homolog of GLP-1R, have revealed key differences between the peptide-free and peptide-bound states, including an interesting -sheet motif in the peptide-free structure comprised of the stalk region and extracellular loop 1 ( ECL1) 9,14

Wang, L., Wang, W., Kaelber, D
