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Furthermore, some patients do not respond to anti-IBD therapy
included a figure showing the two-way influence between GLP-1 and metabolic/lifestyle factors
American Family Physician, 106(6), 638-644

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This precision-wellness approach helps distinguish individual variation from true safety concerns, enabling confident, informed treatment decisions

In 2019, NICE initially did not recommend tisagenlecleucel for pediatric ALL, even though it could be curative, because at 282k (about $350k) it far exceeded UK thresholds
