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The side effects can worsen with increases in dosage
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Significant weight loss from GLP-1 therapy may reduce levothyroxine requirements, necessitating regular thyroid function testing every 36 months during active weight loss

Age Ageing 48(1):1631 [DOI] [PMC free article] [PubMed] [Google Scholar] 3.Xu Y, Hu T, Shen Y, Wang Y, Bao Y, Ma X (2023) Association of skeletal muscle mass and its change with diabetes occurrence: a population-based cohort study

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Women who maintained consistent supplementation (80% adherence) experienced 24% fracture risk reduction -- twice the benefit of inconsistent users
