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Lancet Diabetes Endocrinol (2018) 6:27586

163 In vitro, the abovementioned ER stress/JNK/IRS1 pathway was involved in A 1-42 oligomer-induced tau hyperphosphorylation, which may indicate that IR promotes the role of ER stress in AD

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Lastly, by enhancing insulin sensitivity, they help in better glucose management, which can be crucial for weight loss
