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Increased cytoplasmic Ca +2 triggers mitochondrial ATP generation and insulin exocytosis from insulin granules
The resulting calcium influx and release lead to insulin granule exocytosis, which is supported by mitochondrial ATP synthesis
As such, the study of this complex endocrine organ, might help us to create new pharmacological tools to amend the specific molecular axis that drive T2DM and the associated co-morbidities known to affect the cardiovascular (25, 26) and renal system (27, 28)
Cost and Access Matter for Indian Patients GLP-1 medicines are not one-time decisionsthey are long-term commitments
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