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This dual impact makes these medications a compelling option for managing PCOS

Although oral MTX inhibits keratinocyte overproliferation, the first-pass effect and insufficient skin accumulation lead to reduced bioavailability and systemic side effects 12,14

Rapid weight loss can leave skin looking loose and less resilient, and collagen supplementation may support skin structure during the transition

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however, their use is limited due to side effects

Better Blood Sugar Control : My glucose levels stabilized, allowing me to enjoy life without constant worry