why does semaglutide make me so tired Fatigue: Causes, Effects, and Solutions Explained Why Semaglutide Makes You Tired

"The FDA regulates brand-name GLP-1 drugs such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) and approves those drugs in very specific doses," says Katy Williams, MD, an MU Health Care family medicine doctor and bariatric medicine specialist

Many patients assume they can get the "same medication" (semaglutide or tirzepatide) by having their provider write for the diabetes-approved version

While the connection is not totally clear, experts believe vivid dreams may be one of the side effects of hormonal fluctuations

Patients should also clarify emergency protocols: whom to contact if symptoms worsen, when to seek urgent care, and criteria for temporarily holding semaglutide (such as during severe gastrointestinal symptoms, dehydration, or hospitalization)

The mechanical injury is accompanied by release of cytokines such as interleukin 1 or 6 (IL-1 or 6), with both acute and long-term deleterious cellular effects: necrosis, apoptosis, autophagy and/or senescence [6]

In March 2026, FDA issued 30 warning letters to telehealth companies marketing compounded GLP-1 products, citing claims that those products were equivalent or comparable to FDA-approved drugs, as well as marketing that blurred the line between approved and unapproved therapies