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The pathophysiology involves hormonal influences, immune dysfunction, and inflammatory processesmechanisms that differ substantially from the metabolic pathways targeted by GLP-1 medications

Clinical trials to test for effects of GLP-1s on a range of novel outcomes including alcohol use disorder and Alzheimers disease are already underway

[DOI] [PMC free article] [PubMed] [Google Scholar] [19].Elsworth B

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Clinical trials have shown substantial weight reduction, with participants on the highest dose losing almost 21% of their body weight