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Comparisons of normally distributed data were made using two-tailed Students t-tests

Contrave is not appropriate for patients with a history of seizures, eating disorders, or those taking opioids or MAOIs the naltrexone component can precipitate withdrawal in patients dependent on opioids

The metabolic subtype is more prone to obesity, IR, dyslipidemia, and, making it the primary target population for intervention in this review

19 The Effect of GLP-1RAs on Blood Pressure A meta-analysis of 16 RCTs showed that use of GLP-1RAs leads to a moderate BP reduction in patients with hypertension