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In the STEP-HFpEF and STEP-HFpEF DM trials, semaglutide resulted in modest reductions in SBP (2.9 mm Hg) alongside improvements in symptoms, physical function, and weight

non-users was assessed using Fischer's test, which accounted for groups with sample size 0.7 was the cut-off for correlation

Pico-Cylinders can be filled with vapour-phase (N 2 , Ar) or dual-phase (CO 2 ) gases to a wide pressure range (5350 bar), allowing plunger force and delivery time to be configurable without requiring spring swaps or housing design changes